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ThorneAmino acids & derivatives

Methyl-Guard Plus, 90 capsules

£49.49 for 90 capsules at Healf. It carries more than one active ingredient, so it is not ranked against single-ingredient products. Each price below counts one ingredient only.

What it really costs, per 2.5 g£2.29One 2.5 g dose is our comparison unit for betaine (TMG). It is not a recommendation.
A day£2.29
A week£16.04
A month£68.74
A year£836.29

At one 2.5 g dose a day, this pack lasts 22 days. A month is 30 days, so twelve of them is not quite a year.

How we worked it out

Betaine (TMG)

  • Servings: 90 ÷ 3 per serving = 30
  • In the pack: 30 × 1.8 g = 54 g
  • £49.49 ÷ 54 g × 2.5 g = £2.29 per 2.5 g
  • A week £2.29 × 7 = £16.04 · a month × 30 = £68.74 · a year × 365 = £836.29
  • Amount per serving: stated on the label.

Folate

  • Servings: 90 ÷ 3 per serving = 30
  • In the pack: 30 × 3 mg = 90 mg
  • £49.49 ÷ 90 mg × 400 µg = 22p per 400 µg
  • A week 22p × 7 = £1.54 · a month × 30 = £6.60 · a year × 365 = £80.28
  • Amount per serving: stated on the label.

Riboflavin (vitamin B2)

  • Servings: 90 ÷ 3 per serving = 30
  • In the pack: 30 × 90 mg = 2.7 g
  • £49.49 ÷ 2.7 g × 100 mg = £1.83 per 100 mg
  • A week £1.83 × 7 = £12.83 · a month × 30 = £54.99 · a year × 365 = £669.03
  • Amount per serving: stated on the label.

Vitamin B12

  • Servings: 90 ÷ 3 per serving = 30
  • In the pack: 30 × 3 mg = 90 mg
  • £49.49 ÷ 90 mg × 1 mg = 55p per 1 mg
  • A week 55p × 7 = £3.85 · a month × 30 = £16.50 · a year × 365 = £200.71
  • Amount per serving: stated on the label.

Vitamin B6

  • Servings: 90 ÷ 3 per serving = 30
  • In the pack: 30 × 45 mg = 1.35 g
  • £49.49 ÷ 1.35 g × 50 mg = £1.83 per 50 mg
  • A week £1.83 × 7 = £12.83 · a month × 30 = £54.99 · a year × 365 = £669.03
  • Amount per serving: stated on the label.

The standard dose is a comparison unit, not a recommendation. Always confirm the price on the retailer's site. How we compare everything.

How it compares: betaine anhydrous

All 7, ranked →
TMG Pro PowderCheapest per 2.5 gHealf · 1 g a serving · £8.71 a month · a pack lasts 40 days29p£11.61View at Healf (opens in a new tab)
TMG Betaine 1000mg TabsHealf · 3 g a serving · £10.29 a month · a pack lasts 40 days34p£13.72View at Healf (opens in a new tab)
TMG 1000mgHealf · 1 g a serving · £10.62 a month · a pack lasts 48 days35p£16.99View at Healf (opens in a new tab)
This productHealf · 1.8 g a serving · £68.74 a month · a pack lasts 22 days£2.29shown above

Ranked purely by price per 2.5 g. 53 combination products also contain betaine (TMG).

How it compares: methylfolate

All 22, ranked →
Methyl Folate 1,000 mcgCheapest per 400 µgHealf · 1 mg a serving · £1.27 a month · a pack lasts 7 months4p£9.49View at Healf (opens in a new tab)
5-MTHF 5 mgHealf · 5 mg a serving · £2.22 a month · a pack lasts 2.1 years7p£55.58View at Healf (opens in a new tab)
Vimergy5-MTHFHealf · 5 mg a serving · £2.36 a month · a pack lasts 2.1 years8p£58.99View at Healf (opens in a new tab)
This productHealf · 3 mg a serving · £6.60 a month · a pack lasts 7 months22pshown above

Ranked purely by price per 400 µg. 155 combination products also contain folate.

How it compares: riboflavin-5-phosphate

Compare every product in this form →
Riboflavin 5'-PhosphateCheapest per 100 mgHealf · 36.5 mg a serving · £31.92 a month · a pack lasts 22 days£1.06£23.30View at Healf (opens in a new tab)
This productHealf · 90 mg a serving · £54.99 a month · a pack lasts 27 days£1.83shown above

Ranked purely by price per 100 mg. 53 combination products also contain riboflavin (vitamin B2).

How it compares: vitamin B12 methylcobalamin

All 27, ranked →
WeightWorldVitamin B12 Methylcobalamin TabletsCheapest per 1 mgWeightWorld · 1 mg a serving · 60p a month · a pack lasts 1.2 years2p£8.99View at WeightWorld (opens in a new tab)
Vitamin B12 Tablets 1000mcgBulk · 1 mg a serving · 83p a month · a pack lasts 6 months3p£4.99View at Bulk (opens in a new tab)
Vitamin B12 Tablets 1000mcgBulk · 1 mg a serving · £1.25 a month · a pack lasts 2 months4p£2.49View at Bulk (opens in a new tab)
This productHealf · 3 mg a serving · £16.50 a month · a pack lasts 3 months55pshown above

Ranked purely by price per 1 mg. 218 combination products also contain vitamin B12.

How it compares: vitamin B6 P-5-P

All 4, ranked →
P5P 50Cheapest per 50 mgHealf · 50 mg a serving · £8.55 a month · a pack lasts 6 months28p£51.30View at Healf (opens in a new tab)
P5P 50Healf · 50 mg a serving · £9.00 a month · a pack lasts 2 months30p£18.00View at Healf (opens in a new tab)
Pyridoxal 5'-PhosphateHealf · 33.8 mg a serving · £11.26 a month · a pack lasts 4 months38p£45.69View at Healf (opens in a new tab)
This productHealf · 45 mg a serving · £54.99 a month · a pack lasts 27 days£1.83shown above

Ranked purely by price per 50 mg. 158 combination products also contain vitamin B6.

On the label

Betaine (TMG) · Betaine anhydrous (TMG)
1.8 g per serving (stated on the label)
Folate · Methylfolate (5-MTHF)
3 mg per serving (stated on the label)
Pack
90 capsules · 30 servings · 3 capsule(s) a serving
Cost per serving
£1.65 (30 servings in the pack)
More label details
Riboflavin (vitamin B2) · Riboflavin-5-phosphate
90 mg per serving (stated on the label)
Vitamin B12 · Methylcobalamin
3 mg per serving (stated on the label)
Vitamin B6 · P-5-P (active form)
45 mg per serving (stated on the label)
Sold by
Healf
What the listing says
“90 caps” · “Servings Per Container: 30” · “Serving Size: 3 Capsules” · “Betaine Anhydrous (Trimethylglycine) ; 1.8 g”
Ingredients

Betaine Anhydrous (Trimethylglycine), Riboflavin (as Riboflavin 5'-Phosphate Sodium), Vitamin B6 (as Pyridoxal 5'-Phosphate), Folate (as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt), Vitamin B12 (as Methylcobalamin), Hypromellose (Derived from Cellulose) Capsule, Anti-Caking Agent (Calcium Laurate), Acidity Regulator (Calcium Citrate)

From the Healf listing. Check the pack itself if you have an allergy: labels mark allergens in bold.

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One 2.5 g dose is our comparison unit, not a recommendation.

Price history

No price change since 1 October 2026. Checked on 20 days, most recently 20 October 2026.

Price at every check
£49.49Healf
First recorded
£49.491 Oct
Checked on
20 dayssince 1 Oct
Pack price at each check.
  1. First checked at Healf: £49.49

Questions about this product

How much does Thorne Methyl-Guard Plus cost per 2.5 g?

£2.29 per 2.5 g, from £49.49 for 90 capsules at Healf, checked on 20 October 2026.

How long does one pack last?

22 days at one 2.5 g dose. The pack holds 54 g in total.

How much does Thorne Methyl-Guard Plus cost per 400 µg?

22p per 400 µg, from £49.49 for 90 capsules at Healf, checked on 20 October 2026.

How long does one pack last?

7 months at one 400 µg dose. The pack holds 90 mg in total.

How much does Thorne Methyl-Guard Plus cost per 100 mg?

£1.83 per 100 mg, from £49.49 for 90 capsules at Healf, checked on 20 October 2026.

How long does one pack last?

27 days at one 100 mg dose. The pack holds 2.7 g in total.

How much does Thorne Methyl-Guard Plus cost per 1 mg?

55p per 1 mg, from £49.49 for 90 capsules at Healf, checked on 20 October 2026.

How long does one pack last?

3 months at one 1 mg dose. The pack holds 90 mg in total.

How much does Thorne Methyl-Guard Plus cost per 50 mg?

£1.83 per 50 mg, from £49.49 for 90 capsules at Healf, checked on 20 October 2026.

How long does one pack last?

27 days at one 50 mg dose. The pack holds 1.35 g in total.

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